Dermal fillers are minimally invasive cosmetic injections. They are common aesthetic procedures that usually last anywhere from 6 to 18 months. Dermal fillers contain FDA-approved substances. This plumps the skin, usually with naturally occurring substances like hyaluronic acid. When injected, these substances smooth fine lines and wrinkles. By plumping the skin, filler can also address volume loss. Volume loss is usually a side effect of aging, when the skin doesn't produce as much collagen.